Caymin Chemical’s LDL Uptake cell-based assay kit provides a convenient tool for studying LDL uptake and regulation at a cellular level. The kit employs human LDL conjugated to DyLight 549 as a fluorescent probe for detection of LDL uptake into cultured cells. A LDL receptor-specific polyclonal antibody and a DyLight 488-conjugated secondary antibody are included for identifying the distribution of LDL receptors.
Low-density lipoprotein (LDL) is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL uptake and its regulation are important therapeutic targets for atherosclerosis and related diseases.
