The Pearl Imager leverages Li-Cor’s infrared chemistry and engineering design established with the Odyssey infrared imaging system.
Designed specifically for imaging small animals such as mice, the Pearl Imager starts with dual-channel near-infrared detection for high sensitivity and provides design simplicity with one-button image acquisition. Load a mouse in the unique imaging drawer, push the close button, and in 30 s you’ll have clear, multi-colour images with proper exposure.
The system uses a CCD-based optical system specifically designed for in vivo imaging in the near-infrared (NIR) spectral region, where tissue autofluorescence and light scattering are low. The imager also incorporates a filtering design which greatly reduces noise and signal detection and is optimised for IRDye near-infrared dyes.
NIR laser illumination permits much deeper tissue penetration than white light. Smaller targets can be visualised at greater depths, allowing earlier tumour detection.
Combining the Odyssey infrared imaging system with the Pearl Imager creates a versatile workstation for in vivo and in vitro imaging. Probes developed using an IRDye near-infrared dye can be used for evaluation of binding capacity in vitro, in vivo imaging and tissue imaging.