NanoString Technology nCounter Analysis System

Friday, 08 February, 2013 | Supplied by: Bio-Strategy Pty Ltd

According to Bio-Strategy, the NanoString Technology nCounter Analysis System is set to become a cornerstone technology of molecular biology in the same way PCR has done. It uses colour-coded molecular barcodes that hybridise to and directly detect different types of target nucleic acid target molecules (mRNA, miRNA or DNA).

The novel detection system provides digital multiplex quantification of up to 800 different target molecules in a single sample. It is sensitive to the full range of biological expression, requires very little sample (as little as a single cell) and is resistant to degraded material such as formalin-fixed, paraffin embedded (FFPE) tissue.

In addition to a range of application-specific kits for gene expression, copy number variation (CNV) and miRNA analysis, custom nanoString CodeSets can detect any target sequence from any organism. Compared to qPCR, results are said to be simpler to generate, more precise and more tolerant of poor sample quality.

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