Dolomite Bio nadAROSE and nadia3D hydrogel reagent kits

Dolomite Bio is launching two hydrogel-focused reagent kits, enabling high-throughput encapsulation of cells in hydrogel scaffolds. The kits address the needs of researchers exploring both agarose encapsulation and collagen-based hydrogel projects for the 3D cell culture space.

Current methods for constructing hydrogel scaffolds involve time-consuming ‘home brew’ batch methods, with few commercially available solutions. For this reason, Dolomite Bio is launching the nadAROSE kit for the encapsulation of cells in agarose and the nadia3D kit for 3D cell culture research. Both kits are complete and standardised solutions, containing all the single-use, prefabricated consumables needed for scaffold production on the company’s Nadia Instrument.

Due to the flexible nature of the Nadia Instrument, researchers can perform high-throughput encapsulation of up to 1 million cells in one run, with a choice of running one, two, four or eight lanes in parallel, in under 30 min. The fully automated instrument guides users through all relevant steps of the experiment via an easy-to-use touchscreen interface. With single-use chips and precise temperature control, the instrument is suitable for hydrogel research projects. Additionally, researchers will benefit from the wide sample compatibility, opening up research areas involving large cells of over 50 µm in diameter, such as cardiomyocytes.

Both kits can offer control over monoclonality, giving researchers access to a variety of downstream workflows such as cell secretion studies, cell-cell interactions and microbial cell culture. Furthermore, the nadAROSE kit is compatible with cytometric analyses. The nadia3D kit opens up downstream workflows in the development of novel culture techniques for fastidious cell lines, disease modelling, identification of novel drug targets and pharmaceutical screening.