Dolomite Bio Nadia Go microfluidic system for custom protocol development

Dolomite Bio’s Nadia Go is a compact microfluidic system for custom microfluidic and genomics research. It combines the microfluidic technology underlying the company’s Nadia Instrument with the customisable parameters of Nadia Innovate, granting access to the custom microfluidic protocol development without the necessity of large capital outlay.

Currently most custom microfluidic research is performed using older complex modular systems. These are tricky and time-consuming to set up, and require some level of expertise in microfluidics to be effective. By contrast, the system has a small footprint with no tubing and no PDMS, uses single-use chips and has a semi-automated set-up, with parameters controlled through easy-to-use PC software.

The product is a completely open platform, created with so-called ‘tinkerers’ in mind. Using Dolomite Bio’s core pressure-controlled microfluidics technology, the system enables the development of user-defined single cell protocols and applications. Users can create, change, test and save novel protocols and biological workflows through the adjustment of user-defined parameters such as droplet size, droplet frequency, temperature, agitation and timing. Droplet formation can also be observed in real time with the product’s high-speed microscope and camera for easy process visualisation. This gives researchers freedom from standard protocols and applications, as well as the liberty to create and share novel protocols with other users.

Designed to make microfluidics accessible to an even greater number of researchers, the product is relevant to any lab interested in custom microfluidic research, or looking to complement research performed using standardised applications on other instruments for single-cell research.