DiaSorin Liaison Iam analyser and assays

The Liaison Iam is a small benchtop unit which is connected to the Iam Control Unit (ICU) via a USB interface. The ICU runs proprietary software in which a GUI guides the operator through a series of simple set-up steps. Up to six instruments can be connected to a single ICU, making the product suitable for laboratories that may start with a small number of tests and add units as their workload or test portfolio grows.

The analyser uses Q-LAMP technology, which offers the benefits of isothermal LAMP technology while adding the advantages of real-time, fluorescent, multiplexed amplification as well as single tube RNA amplification. Analysers running DiaSorin Q-LAMP assays offer an alternative to PCR in decentralised laboratory settings. Such assays include Iam BKV, an in vitro diagnostic assay for the quantification of clinically relevant subtypes of BK virus in human plasma and urine; and Iam VZV, an in vitro diagnostic assay for the detection of clinically relevant subtypes of Varicella zoster virus in human CSF and vesicle swabs.

The benefits of the Q-LAMP approach over conventional PCR are: speed of reaction and time to result; specificity - up to six unique recognition events per reaction; less complex instrumentation - as the Q-LAMP process is isothermal there is no requirement for rapid thermal cycling and instrumentation can be designed accordingly; suitable for use in decentralised facilities where speed of result and turnaround time are important; small footprint instrumentation.