Bio-Rad ddPCR KRAS Screening Multiplex Kit

Bio-Rad Laboratories has launched the ddPCR KRAS Screening Multiplex Kit, the latest offering in the company’s Droplet Digital PCR line of predesigned, fully wet-lab validated assays. The kit offers improved sensitivity and simultaneous detection of the seven most common KRAS mutations in a single ddPCR experiment.

KRAS mutations are found in 90% of pancreatic cancer cases and 30% of colorectal cancer cases, making it a gene of interest to cancer researchers. Used with Bio-Rad’s ddPCR technology, the multiplex kit is able to detect and quantify extremely low levels (down to 0.2%) of KRAS mutant DNA in a single assay. Cancer samples are often available in limited quantities, and the kit enables researchers to derive results from low amounts of starting material.

The product delivers a simple yes/no answer as to whether a KRAS mutation exists in smaller samples. It allows researchers to screen for multiple mutations in a single reaction, saving time and resources. The kit is compatible with all of Bio-Rad’s Droplet Digital PCR Systems, including the QX200 AutoDG Droplet Digital PCR System.