Articles
Metabolomics - an important emerging science
As with any emerging science there is some controversy regarding nomenclature, but the newly formed Metabolomics Society seems to be adhering to a convention consistent with the other '-omic' sciences
[ + ]Adjuvants: The problem with peptides and the DCtag advantage
Vaxine's Nikolai Petrovsky says peptide vaccines work well in highly inbred laboratory mice, but have consistently failed in clinical trials over the past two decades because humans are an outbred species. [ + ]
Adjuvants: the players
Several Australian companies are trialling new 'natural' and synthetic adjuvants that combine potent immuno-stimulatory activity with low toxicity. Australia's biggest biotech, Melbourne's CSL (ASX:CSL), is boosting its experimental vaccines with its Iscomatrix adjuvant system, a phospholipid-cholesterol formulation containing a purified saponin extract from the bark of the South American tree Quillaja saponaria. [ + ]
Adjuvant technology: a powerful brew
Shakespeare's witches, in 'Macbeth', were concocting mischief, not some nostrum to ward off plague, but some of the things that imbue today's vaccines with immunogenic fizz would not have been misplaced among the eldritch ingredients in their cauldron. [ + ]
Corporate governance can be biotech's Achilles' heel
Some Australian biotechs are getting creative with company structure. But analysts prefer their companies to play it straight. [ + ]
Cell culture mapping system
In a recent project, electrophysiology researchers at Westmead Hospital in Sydney required a system to acquire and analyse signals measured using a micro-electrode array
[ + ]Better sampling, more analyses, bigger laboratories?
I'm a statistician. I don't know a mass spectrometer from a resonating horoscope. But it seems to me that many practitioners and researchers do not have an optimal balance between the various stages of their data collection
[ + ]Planning for technology change
How effective LIMS software design can leverage evolving technologies to reduce risk and improve ROI. As the commercial LIMS marketplace evolves and matures, it continually faces the challenge of technology change
[ + ]Superacid - The world's strongest acid uncovered
Researchers at the University of California, Riverside have discovered the world's strongest acid. Remarkably it is also the gentlest acid
[ + ]Venture capital investment picks up the pace
Australian venture capitalists invested more than $1 million per week in Australian biotechnology in the past financial year, an increase on the previous year and a recovery to the historic level of two years ago. As in the past, a large portion of the investment was made by a small number of investors, and was received by a small number of investees. [ + ]
The rapid detection of light hydrocarbons
GeoVOC represents a new approach to near-surface geochemical petroleum prospecting. Developed in conjunction with petroleum prospecting companies, GeoVOC uses SIFT-MS to reduce sample analysis time from up to thirty minutes to less than thirty seconds
[ + ]Crystallisation in silico - Figuring out the structures of biological macromolecules
When Francis Crick and James Watson deciphered the structure of DNA in 1953, x-ray crystallography became famous. X-ray crystallography has long since become the workhorse for structural studies of big biological molecules
[ + ]Does your lab have it all?
What's New Magazines and Science Industry Australia Inc (SIA) invite entries to the Laboratory of the Year competition. All new or renovated laboratories completed and occupied between 1 January 2002 and 31 December 2004 are eligible to enter
[ + ]The end of the BIF boom?
With Biotechnology Innovation Fund and R&D Start grants rolled into the new Commercial Ready, the Australian biotech sector may face a post-BIF bust, writes Michael Vitale. [ + ]
Partner or perish
At a recent conference in Sydney, biotechs and big pharma came together to explore how they should work together. Renate Krelle was there. [ + ]