Malvern Viscotek light-scattering GPC/SEC detectors

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Light-scattering GPC/SEC detectors are powerful tools for protein, polymer and macromolecular research commonly used to determine absolute molecular weight and protein aggregation. While most SEC systems use a single concentration detector, the addition of various light-scattering detectors enables the measurement of molecular weight independent of retention volume.

Right-angle light scattering (RALS) detectors enable molecular size to be measured for small isotropic scattering molecules (below ~15 nm) while low-angle light scattering (LALS) detectors allow larger molecules to be measured. Multi-angle light scattering (MALS) can be used to measure the radius of gyration (Rg).

The most appropriate technology to use can depend on application as well as preference. The addition of the Viscotek SEC-MALS 20 to Malvern’s range of detectors is said to make the company the sole provider of every commercially available light-scattering technology for GPC/SEC.

The Viscotek SEC MALS 20 delivers good performance which can be added to any existing GPC/SEC set-up. Claimed to have the greatest number of high-quality detectors (particularly at low angles) of any commercially available MALS detector, the product offers an innovative optical cell design and delivers high sensitivity for all molecule types.