PCO Imaging pco.edge 4.2 back-illuminated sCMOS camera for microscopy

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The pco.edge 4.2 back-illuminated sCMOS monochrome camera from PCO Imaging is suitable for applications involving brightfield and fluorescence microscopy, light sheet microscopy, calcium imaging, FRET, FRAP, SIM, digital pathology, single-molecule localisation microscopy, lightsheet fluorescence microscopy (LSFM), high-speed bright field ratio imaging, high throughput screening, high content screening, biochip reading, TIRF microscopy, spinning disk confocal microscopy, ophthalmology, bioluminescence and chemoluminescence.

The pco.edge 4.2 bi camera comes with high resolution of 2048 x 2048 pixels, a 6.5 x 6.5 μm² pixel size for high-quality images and quantum efficiency up to 95%. It incorporates a powerful USB 3.1 Gen 1 interface and a flexible cooling system, allowing the use of air or water to cool the sensor down to -25°C. At this temperature, the dark current is reduced to 0.2 e-/pixel/s. The pco.edge bi offers 40 fps maximum frame rate at full resolution.

The camera system is compact and designed for users who require high quantum efficiency, good 16-bit dynamic range, high frame rates, long exposure times and ultralow readout noise. The camera offers exposure times from 10 μs to 20 s and it also offers lightsheet scanning mode via SDK.