Shimadzu LCMS-8050 triple quadrupole LC-MS/MS

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Shimadzu introduces the LCMS-8050 triple quadrupole mass spectrometer. The device features high-sensitivity quantitation delivered at high speed, multicomponent analysis performed rapidly and simultaneous quantitative and qualitative analyses.

The product’s performance is a result of the further development of the company’s ultrafast MS technologies such as UF Switching, UF Scanning and UF MRM. Combined with advances in sensitivity, the unit delivers high performance and detectability for trace-level multianalyte analysis. Advances include 5 ms polarity switching, true 30,000 µ/s scanning and 555 MRM transitions/s.

The sensitivity gains deliver attogram-level reproducible quantitation for Verapamil, demonstrating the utility of the instrument for trace clinical applications and environmental applications without the need for sample pre-concentration. This has been achieved with a small inlet orifice that doesn’t require higher vacuum pumping capacity, resulting in lower maintenance and cleaning and a lower cost of ownership of the instrument over its lifetime.

Design innovations include tool- and cable-free source changeover. The source is robust and requires minimal adjustment. User maintenance and cleaning is simplified with an accessible API source area and a desolvation line that can be removed without breaking MS vacuum.