Bio-Rad Laboratories Foresight Pro Columns

Bio-Rad Laboratories has launched its Foresight Pro 45 cm inner diameter (ID) chromatography columns, designed to support downstream process-scale chromatography applications across different stages of biological drug production. Expanding on the company’s portfolio of columns with inner diameters ranging from 5 to 33 cm, the larger 45 cm ID Foresight Pro Column offers biopharma manufacturers an easily integrated solution for downstream purification of biomolecules, including vaccines, antibodies and recombinant proteins.

The columns are manufactured and packed in a controlled ISO Class 7 cleanroom, providing GMP readiness. The standardised design and format, in a range of diameters and bed heights, offers a convenient solution, packed with either CHT Ceramic Hydroxyapatite Media Type I, Type II or XT. Bio-Rad’s CHT Media is a rigid mixed-mode support media for biomolecule purification, with a novel composition — Ca₁₀(PO₄)₆(OH)₂ — that allows biomolecules to interact with the media by means of metal affinity interactions via calcium atoms and/or cation exchange interactions via phosphate groups.