Complex biopolymer characterisation

The Malvern Viscotek TDAmax gel permeation/size exclusion chromatography (GPC/SEC) system is an information-rich, time-efficient analytical solution for the comprehensive characterisation of complex food ingredients and additives based on polysaccharides. The system features a fully integrated triple detector array that includes a low angle light scattering detector (LALS), four-capillary differential viscometer and refractive index detector.

Using GPC/SEC, passing a sample through a series of carefully specified packed columns separates it on the basis of hydrodynamic size. Single or multiple detectors analyse the resulting fractions. The design and selection of the detectors dictates how much information can be gathered during each experiment.

The TDAmax detector array provides absolute molecular weight without extrapolation or correction, molecular size and intrinsic viscosity, as well as information on structure, conformation, aggregation and branching. Adding an additional UV/vis detector creates an integrated tetra detector array suitable for copolymer characterisation.