Grace ProVance pre-packed columns

WR Grace & Co has introduced ProVance prepacked Protein A columns for purification of biologic drugs, specifically monoclonal antibodies (mAbs). The columns bring together Protein A resin and a convenient prepacked column format designed specifically for facilities sites that have moved to single-use manufacturing methodologies.

The portfolio of disposable columns comes prepacked with a silica-based Protein A resin claimed to have a higher capacity than alternative technology used for mAb purification. Biopharmaceutical users are said to have confirmed 40 to 60% total operational cost reduction with the columns by eliminating time-consuming cleaning and packing steps and achieving increased efficiency. The prepacked disposable columns further improve biopharmaceutical productivity by lowering the risk of contamination and accelerating time to market.