IonOpticks Aurora Frontier UHPLC column for proteomics applications

Proteomics provides a greater understanding of the complexity of life than other forms of in-depth biological research approaches, as it provides deep insight into the structure and function of proteins and how they react within the cell in response to their environment. IonOpticks has developed the Aurora Frontier UHPLC column to meet the demands of users and mass spectrometry vendors who wanted better separation of samples, providing the opportunity to understand the proteome at greater depths than mass spectrometry has achieved before.

The product is a 60 cm nanoflow UHPLC packed emitter column and offers high performance using long sample gradients, which should enable researchers to get more depth of coverage due to its good peak capacity when compared to other nanoflow chromatography. It is claimed to produce more than 10,000 unique protein IDs, over 25% more than the next highest performing commercially available column for single species samples.

The device allows researchers to get as much as possible from their samples, which are often precious and labour-intensive to generate. Having a deeper understanding of the proteome will help with understanding disease, defining opportunities for early diagnosis, in addition to increasing the capacity to identify targets and monitor outcomes for the benefit of therapy intervention.