Supelco Ascentis Express 2.0 micron UHPLC column line

Supelco has launched the Ascentis Express 2.0 micron, a high-speed, ultrahigh-performance liquid chromatography (UHPLC) column platform based on the fused-core particle design. Ascentis Express 2.0 micron fused-core particles are designed to provide UHPLC performance while addressing the disadvantages in existing sub-2 micron UHPLC columns.

The columns deliver 300,000 plates/m efficiency and are less susceptible to column plugging due to the large 1.0 μm frits on the column inlet. While the columns can be used up to 1000 bar (14,500 psi), they are said to produce approximately 20% lower back pressure than most commercially available sub-2 μm UHPLC columns under the same conditions, reducing concerns of column frictional heating and instrument wear and tear associated with very small particles.

The product line has expanded to 2.0, 2.7 and 5 micron particle UHPLC columns. The range is scalable from UHPLC to legacy HPLC systems, assuring researchers that their methods can be seamlessly transferred across campus or around the world. Ascentis Express 2.0 is available in 11 different dimensions and two introductory phases - C18 and F5.