TILL Intravital^2P two-photon microscope

The Intravital^2P is an upright two-photon laser scanning microscope specifically created for the imaging of living tissues and animals at low laser power.

The microscope frame is designed around a very short, large-diameter, dual-emission detection beam path. Collecting lenses further increases the share of light that falls onto the GaAsP detectors, which are hand-selected for >40% quantum efficiency and very low noise and dark current. The resulting signal detection performance facilitates imaging at low light levels and improves signal-to-noise ratio, allowing fast measurements deep within highly scattering tissue.

Imaging is achieved in up to six separate colour channels by use of the dual-colour, non-descanned detection system and the three-position motorised filter slider. The modular XY stage design with adapters is suitable for everything from slides to animals.