Waters Aquity UPLC CSH130 C18 and XSelect HPLC CSH130 C18 columns

Waters Corporation’s CSH130 particle technology columns offer selectivities for UPLC and HPLC peptide mapping and proteomics applications. The Aquity UPLC CSH130 C18 and XSelect HPLC CSH130 C18 Columns are suitable for the analysis and purification of peptides for the quality of information generated by UPLC and UPLC/MS assays. The columns are available in a variety of particle sizes and column dimensions.

The columns feature the company’s synthesis process for its charged-surface hybrid particles, which imparts a low-level positive charge to the surface of each particle. The technology allows the columns to be used with a weaker acid modifier, such as formic acid, to obtain greater resolving power and improved method sensitivity compared to standard LC/MS methods that specify the use of MS signal-suppressing ion pairing additives such as trifluoroacetic acid (TFA).