Waters Patrol UPLC Laboratory Analyzer

The Waters Patrol UPLC Laboratory Analyzer has been designed to meet the needs of process development laboratories for real-time quality analytical data. Built on the company’s ultra performance LC (UPLC) technology, the system provides scientists with mission-critical analytical data to guide decision-making at the earliest stages of manufacturing process development.

With the introduction of the analyser, scientists can now deploy real-time LC in an automated manner for process-related data acquisition and decision-making on two new fronts: on the manufacturing floor with the analyser and, now, in the process development laboratory.

Designed and engineered to perform lab to pilot-scale online and at-line reaction monitoring in the process development laboratory, the analyser system provides accurate, reproducible and precise chemical-reaction mapping across the entire time course of the process. With real-time LC and LC/MS information, users are able to fully characterise reaction kinetics and determine which process produces the desired endpoint.

A major feature of the system is its dilution accuracy, linearity and range. The technology behind this performance is the instrument’s process sample manager (PSM) that automatically extracts an online sample from a reactor or slipstream, performs sample prep and sample injection - a process that once required the time and full attention of an analytical technician. In addition to online samples, the PSM can also accept and store up to 32 barcode labelled vials, which can be a combination of different standards, controls and at-line samples.