Proteintech Uni-rAb Recombinant Monoclonal Antibodies

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Uni-rAb antibodies are the latest generation of recombinant monoclonal antibodies developed using Proteintech’s Antigen-Specific B-Cell Cloning & Engineering (ABCE) platform. The platform achieves stable and high expression of recombinant monoclonal antibodies by cloning antibody heavy and light chain sequences derived from antigen-specific B cells into high-yield expression vectors followed by their introduction into suitable mammalian expression systems.

Antigen-specific single B cell sorting allows the isolation of functional monoclonal antibodies reactive against antigens in their native conformation that predominantly occur in vivo and are difficult to reproduce in vitro. This ultimately leads to the generation of Uni-rAb recombinant antibodies that have native V_H-V_L pairings, which is critical for maintaining antibody specificity and functionality but is often lost in other antibody development approaches such as phage display.

Uni-rAb recombinant monoclonal antibodies offer high lot-to-lot consistency, specificity and affinity, and are available in carrier-free formulations.

For further information, contact United Bioresearch Products, the distributor of the full range of Proteintech products in Australia, or visit https://www.ptglab.com/products/recombinant-antibodies/.