High specificity clonal antibodies

Wednesday, 08 July, 2009 | Supplied by: http://www.dbbiotech.com/index.php

DB Biotech has introduced a new technology for the production of highly specific RABBIT CLONAL antibodies. In vitro cloning technology developed by the company enables the preparation of a pure immunoglobulin fraction corresponding to a single clone of B lymphocytes.

The obtained immunoglobulin recognises one single linear epitope on the antigen molecule; therefore making this new type of antibody comparable quality-wise to its monoclonal analogue.

Moreover, the influence of the protein tertiary structure — frequently present in epitopes formed during production of monoclonal antibodies — is eliminated in immunoglobulins corresponding to the clonal antibody.

In this case, the produced antibody corresponds strictly to the conserved linear epitope of the antigen molecule.

Current antibodies include: Actin, p53, iNOS, Protein Kinase C, Erk, Trypsin, CD20, Cytokeratin & Progesterone Receptor.

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