Merck ColorWheel flow cytometry antibodies and dyes

Merck has announced its ColorWheel flow cytometry portfolio, utilising a proprietary technology optimised for flow cytometry that allows users to independently select antibodies and dyes for assembly in any desired combination. The output of these mix-and-matched antibodies and dyes is analogous to a primary conjugated antibody.

The portfolio addresses the fact that multiplexing in flow cytometry can be a puzzle that researchers must piece together, which includes the configuration of the instrument, balancing antigen expression with dye brightness and antibody–dye combination availability. If it is not possible to fit all these factors into one experiment, researchers need to compromise; the portfolio is designed to put more flexibility, productivity and control into their hands to overcome these constraints.

The antibodies and dyes make it easy to build a new multiplex assay for samples with varying expression levels of antigen. One may simply mix and match antibodies and dyes at the bench, in a ready-to-use, convenient format that fits what is best for the sample and the instrument — with a low amount of time and effort required, and removing the need for any labelling kits.