ProBioGen and Thermo Fisher Scientific Gibco Freedom ExpiCHO-S Kit

ProBioGen and Thermo Fisher Scientific have teamed up to develop the Gibco Freedom ExpiCHO-S Kit. The kit allows users to generate cell lines suitable for clinical development without their own starter cells, vectors or prior experience in the field.

The kit uses Thermo Fisher’s ExpiCHO-S cell line and a powerful media platform specifically developed for it. The kit is based on a novel set of ProBioGen vectors equipped with strong promoters, selection markers and protective elements providing expression stability. Together with a simple workflow optimised by ProBioGen, the kit provides short development time, reproducibly high titres (3–5 g/L) and high expression stability.

Generating a stable and high-performing cell line is the starting point for successful pharmaceutical development. With this in mind, the kit allows a seamless transition from transient to stable production reproducing previously found product modifications. Moreover, the specific ProBioGen vector composition offers flexibility not only for antibodies but in particular for a variety of novel product formats.