Thermo Fisher Scientific Gibco Human Plasma-like Medium (HPLM)

Thermo Fisher Scientific has launched the Gibco Human Plasma-like Medium (HPLM) — a cell culture medium that mimics the metabolic profile of human plasma, providing researchers with a realistic view of cell growth within the human body.

The medium contains the same salt concentrations found in human plasma, as well as the same concentrations of over 60 polar metabolites, such as amino acids, nucleic acids, sugars and small organic acids. By resembling the natural cellular environment found in the body, it provides researchers the ability to study the impact of physiologically relevant cell media on their specific research applications, including cancer and other diseases.

When supplemented with foetal bovine serum (FBS), the medium can support cell growth and viability that are comparable to that of conventional basal media formulations supplemented with FBS. For most cell lines, adaptation is not required to transition from conventional medium to HPLM.