GeneCopoeia OncoSpot Cancer Cell Lines

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GeneCopoeia offers premade cancer cell lines carrying diverse gene mutations commonly seen in tumour biomarkers, including EGFR, KRAS and BRAF in the MAPK pathway.

The mutant cells are engineered based on the HCT116 cancer cell line, in which mutations are integrated either homozygously or heterozygously using CRISPR technology. They can be used to enhance our understanding of cancer biology and the development of cancer therapies, either as cell line models for the study of metabolic and signalling pathways or as in vitro models for drug screening and toxicity studies.

The cell lines feature puromycin resistance for easy growth and maintenance. Mutations are available in both homozygous and heterozygous forms. Premade cell lines are available for next-day shipping; a custom cell line service is also available.

For more information: http://www.genecopoeia.com/product/cell-biology-product/cancer-mutant-cell-lines/.