Kuhner microTOM OTR measurement system for microtitre plates

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The Kuhner microTOM (micro-scale Transfer-Rate Online Measurement) is a next-generation online monitoring system for analysing cellular respiration in microbial and cell culture applications directly in 96- or 24-well microtitre plates. Using oxygen transfer rate (OTR) as a precise and scalable indicator, the product offers automated, label-free screening without manual sampling, offline analysis and interruptions.

The Kuhner microTOM stands apart due to the use of 96 parallel OTR measurements, resulting in high throughput for microplate-based cultivation. With low running costs, compact design and high sensitivity, it is suitable for microbial and mammalian cultures, offering robust, scalable data and full compatibility with all Kuhner shakers and FeedPlate.

Two application-specific modules are available: the Kuhner microTOM Type M (microbial) for non-humidified incubators, featuring integrated humidification and aeration, and the Kuhner microTOM Type C (cell culture) for humidified incubators with or without CO₂ control, using incubator air for aeration.

The product quantifies cellular activity every 20 min via OTR. It is non-invasive, probe-free, and unaffected by turbidity or morphology. Independent of shaking conditions and oxygen solubility, it correlates directly with substrate consumption and viable cell count, making it suitable for clone screening, media optimisation, toxicity studies, process development and scale-up validation.

The Kuhner microTOM is designed to offer precise, high-throughput OTR monitoring in standard microtitre plates with low costs and no manual labour. Get in touch with Capella Science now on (02) 9575 7512 or visit here to learn more.