Enzo Life Sciences PD-1 recombinant protein

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PD-1 (programmed cell death-1), also known as CD279, is a transmembrane protein important for regulating immune responses. It is a member of the CD28/CTLA-4 family of immunoreceptors and is expressed on T cells and pro-B cells, suggesting it has a broad spectrum of immune regulation. Human recombinant PD-1 is now available from Enzo Life Sciences in 50 µg packs.

PD-1 with its two ligands, PD-L1 and PD-L2, prevent the activation of T cells and protect tissues from autoimmune attack. PD-1 and its ligands are also involved in reduction of infectious immunity, as well as tumour immunity. PD-1 has been shown to facilitate chronic infection and tumour progression. Drugs targeting PD-1 have shown promise in treating cancer and HIV and may be important in a variety of immune-related disorders.

For more information: http://www.enzolifesciences.com/ENZ-PRT190.