AdipoGen’s Erythroferrone (human) ELISA Kit is a sandwich assay based on two antibodies for the in vitro quantitative determination of human erythroferrone in cell culture supernatants, serum and plasma.
Erythroferrone (also called Myonectin, CTRP15, Fam132B or ERFE) is a hormone produced by erythroblasts in the bone marrow in response to erythropoietin, therefore controlling iron storage levels. It also acts as a myokine, abundantly expressed in skeletal muscle tissue, which is upregulated in response to exercise. Erythroferrone is a potential clinical biomarker for assessing erythropoiesis in patients with blood disorders, iron homeostasis and metabolic disorders.
The levels of erythroferrone measured by the ELISA kit in serum and plasma correspond to erythroferrone mouse protein levels (~500 ng/mL). The kit is highly specific and has a high sensitivity of 270 pg/mL.
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