AdipoGen PD-1/PD-L1 ELISA Kits

AdipoGen has released PD-1/PD-L1 (Programmed Cell Death Protein-1/Programmed Cell Death Ligand-1) ELISA Kits for the detection of PD-1 and PD-L1 in biological fluids.

Regulation and activation of T lymphocytes depend on signalling by the T cell receptor (TCR) and also by co-signalling receptors that deliver negative or positive signals. The PD-1/PD-L1 signalling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. Blockade of the PD-1/PD-L1 interaction enhances anti-tumour immunity. The PD-1 pathway plays a major role in the inhibition of self-reactive T-cells.

AdipoGen’s PD-1/PD-L1 ELISA kits are sensitive and quantitative tools for the measurement of important immune checkpoint biomarkers. The PD-1 (human) ELISA kit detects soluble PD-1, a biomarker for immuno-oncology and autoimmune diseases. The PD-L1 (human) ELISA kit detects soluble PD-L1, a tumour biomarker for poor survival prognosis.