Agilent GenetiSure Pre-Screen Kit oligonucleotide microarray

Agilent Technologies has introduced the GenetiSure Pre-Screen Kit, a high-throughput oligonucleotide microarray for screening aneuploidy and other genomic aberrations in the 5 to 10 Mb range from single cells in three- and five-day embryos.

The kit allows for a turnaround time of less than 8 h from DNA extraction to data analysis. The kit consists of a microarray that can run up to 14 samples and two reference samples simultaneously, so more embryos can be screened without significantly increasing costs. The company’s microarray data can show small, few-megabase microdeletions that are difficult to detect at a single-cell level.

The array is based on Agilent’s technology for high-resolution oligonucleotide comparative genomic hybridisation. The kit contains all necessary reagents to enable whole-genome amplification and labelling of single cells. The microarray is compatible with the company’s CytoGenomics software (version 3.0 or higher) for easy data analysis.