Bio-Rad Laboratories Vericheck ddPCR Empty-Full Capsid Kit

Thursday, 10 October, 2024 | Supplied by: Bio-Rad Laboratories Pty Ltd


Bio-Rad Laboratories has launched its Vericheck ddPCR Empty-Full Capsid Kit for the determination of capsid titre, genome titre and percentage of full capsids in purified or unpurified (crude lysate) AAV samples.

AAV vectors are a powerful gene therapy tool, but their production can result in the generation of product-related impurities, such as partial or empty capsids, which impact effectiveness and can elicit unwanted immunotoxicity. Determining the ratio of full, partial and empty capsids is a recurring challenge throughout AAV gene therapy manufacturing, from early-stage development to quality control and release testing.

The kit is designed to deliver precision and specificity, along with ease of use and high-throughput capabilities, to provide users with a comprehensive solution for AAV vector characterisation and to help drive the advancement of safe and effective gene therapies. Using Bio-Rad’s Droplet Digital PCR technology, it analyses minimal amounts of either crude lysate or purified samples to deliver robust, reproducible data for assessment of AAV vector quality.

Designed for use on the company’s Droplet Digital PCR Systems, the kit enables optimisation of AAV vector characterisation processes to streamline gene therapy development and production while supporting compliance with regulatory guidelines.

Online: www.bio-rad.com
Phone: 02 9914 2800
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