Biolog MitoPlates for mitochondrial function assays

The Biolog MitoPlate S-1 and MitoPlate I-1 enable a comprehensive scan of mitochondrial function.

Mitochondria are organelles inside of human and other eukaryotic cells that produce most of the energy that cells need to survive and grow. When different cell types have mitochondrial defects, it can lead to wide-ranging energetics-related disorders including cancer and ageing, neurological disorders, metabolic disorders and immunodeficiencies.

Biolog’s preconfigured 96-well MitoPlates provide powerful analytical tools leading to a comprehensive assay approach. The MitoPlate S-1 measures metabolism of 31 substrates, most of which are metabolised via the mitochondria. The MitoPlate I-1 measures sensitivity of the mitochondria to 22 diverse mitochondrial inhibitors. Rate of energy production measurements are made and analysed using Biolog’s OmniLog instrument and companion software. The plates can also be read using any microplate reader that offers kinetic reading capability, thus making the assays accessible to most laboratories.

The products further expand Biolog’s broad portfolio with permeabilised cell mitochondrial assays. All of these assays can be read on the versatile OmniLog instrument.