Creatinine is a degradation product of creatine and creatine phosphate, which are involved in the creatine kinase reaction that is a source of phosphate for the conversion of ADP to ATP for energy in cells and tissues that consume ATP rapidly, such as skeletal muscle and the brain. Plasma levels of creatinine have been used as a marker of acute kidney injury, while serum and urinary levels have been used as measures of the glomerular filtration rate (GFR) to assess renal function, estimate and monitor the extent of functional impairment, and detect renal disease.
Cayman Chemical’s Creatinine ELISA Kit is a competitive assay that can be used for the quantification of creatinine in plasma, serum and urine. The assay has a range of 0.273–35 µg/mL, with a midpoint (50% B/B0) of 2.5–5.5 µg/mL and a sensitivity (80% B/B0) of approximately 1 µg/mL. The kit provides rapid assay results in 2.5 h.
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