Cayman Chemical Cysteinyl Leukotriene ELISA Kit
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid via the 5-lipoxygenase (5-LO) pathway in leukocytes. LTC4, LTD4 and LTE4 are collectively referred to as cysteinyl leukotrienes (CysLTs). LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability and are vasoconstrictors of coronary arteries. The biological activity of LTE4 is much lower in most systems studied, but its presence reflects the prior existence of LTC4 and LTD4.
Cayman Chemical’s Cysteinyl Leukotriene ELISA Kit is a competitive assay based on a proprietary high-affinity monoclonal antibody that can be used for quantification of CysLT in urine and other sample matrices. The assay has a range from 8.6–2500 pg/mL and a sensitivity (80% B/B0) of approximately 40.5 pg/mL.
Phone: 02 9698 2022
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