Cayman Chemical offers tools for detecting ferroptosis, a form of cell death caused by iron-dependent lipid peroxide accumulation.
Ferroptosis has been implicated in diseases of the brain, kidneys, liver and heart, and is important to controlling the oxidative stress response. Although the morphological appearance of cells undergoing ferroptosis differs only subtly from apoptosis and necroptosis, the process is distinctly different in its underlying biochemistry.
Cayman provides several key inducers and inhibitors to better understand the ferroptotic pathway. Reagents and assay kits are available to measure both glutathione and the activity of glutathione peroxidase in cells. Oxidised lipid standards and lipid peroxidation assays and probes are also available.
Phone: 02 9698 2022
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