Cayman Chemical Lysosomal Staining Kit (Red Fluorescence)
Cayman Chemical’s Lysosomal Staining Kit (Red Fluorescence) is a convenient tool for imaging lysosomes in live cells. The kit utilises a red fluorescent dye that permeates the lysosomes based on pH gradient. Once protonated, the dye is unable to leave the lysosome, resulting in enhanced fluorescence.
The kit includes bafilomycin A1, which is an inhibitor of the vacuolar ATPase. Treatment with bafilomycin A1 results in decreased lysosomal fluorescence upon staining with the lysosomal staining reagent.
Lysosomes are intracellular organelles that contain enzymes used for the hydrolysis of waste materials and other cellular debris. The pH of the lysosome is ~4.5 to 4.8 and is optimal for these hydrolytic enzymes. The lysosomal pH gradient is maintained through vacuolar ATPases which pump protons into the lysosomes.
Phone: 02 9698 2022
Lonza TheraPEAK AmpliCell Cytokines and TheraPEAK 293-GT Medium
The products provide researchers and manufacturers with high-performance, scalable and...
Grace Bio-Labs protein microarray tools
Grace Bio-Labs' microarray substrates provide high binding capacity and enable high assay...
Siemens Healthineers 3gAllergy assay
Siemens Healthineers has expanded its 3gAllergy assay menu with nine additional component...
