DNA plasmid vectors

Oxford Genetics provides a catalogue of DNA plasmid vectors for researchers. To simplify genetic engineering, the products are based on the same core plasmid backbone (SnapFast) and contain a comprehensive range of DNA components in different configurations.

The aim was to engineer a DNA plasmid system that could accommodate most of the functional DNA inserts that a researcher might require within a single plasmid. By optimising the starting vector, every component of the system can be removed and exchanged for hundreds of other DNA sections which have been pre-designed and tested by Oxford Genetics.

All constructs have been pre-screened for poor codon usage and conflicting restriction sites. Rare codons and restriction sites have been removed to enable efficient expression which ensures conflicting restriction sites do not limit the cloning of other SnapFast DNA inserts.

Most of the DNA sections within the plasmids are flanked by restriction sites of 6 bp in length, with strategically placed 8 bp restriction sites at key positions throughout the plasmid to maximise the versatility of the system.

The plasmids are designed to allow the creation of complex DNA expression vectors with minimal cloning steps. They are a suitable toolset for synthetic biology applications creating versatile cloning systems that deliver results, regardless of a project’s complexity.