Functional protein array

Friday, 08 December, 2006 | Supplied by: http://www.sigma-aldrich.com/



The Panorama Human Signal Transduction Protein Array, developed in conjunction with Procognia Ltd, contains 259 full-length proteins that are involved in key cellular processes including proliferation, differentiation and apoptosis.

This array employs a fusion tag that has been shown to confer protein functionality and that also serves to select, tether and uniformly orientate proteins on a streptavidin-coated glass slide. This technology offers the advantage of allowing proteins to behave in a sterically unencumbered manner, thereby increasing the potential for acquiring data that is more closely representative of native physiological states.

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