Human gene array

Affymetrix has released the GeneChip Human Gene 1.0 ST Array, the latest addition to its Whole-Transcript (WT) assay-based gene expression product family. With the Human Gene 1.0 ST Array design, each of the targeted 28,869 genes is interrogated by an average of 26 probes targeting exon content spread across the entire length of each gene.

The WT assay provides for labelling across the entire length of the transcript, thereby removing the limitations of 3'-based labelling assays. As a result, the Gene 1.0 ST Array measures the total transcriptional activity of the gene in question, delivering a more complete and accurate view of gene transcription.

Following profiling on the Gene 1.0 ST Array, researchers have the additional option to run their WT-labelled samples on the Exon array for analysis of alternative splicing and exon skipping. The Human Gene 1.0 ST Array provides a cost-effective solution to obtaining a more accurate view of gene expression. Gene 1.0 ST Arrays are available for human, mouse and rat.