Intracellular RNA stabilisation

PreAnalytiX has received marketing clearance from the US Food and Drug Administration for the automation of the PAXgene Blood RNA System on the QIAcube. This clearance enables laboratories to automate an IVD purification method which is part of an integrated IVD blood collection method for intracellular RNA.

Automation accelerates processing, increases capacity and helps to standardise processes in the laboratory thus reducing the potential for human error. It also reduces the risk of user-to-user variability and minimises manual tasks performed by technicians allowing them to focus time on other activities.

The PAXgene Blood RNA System can be used to stabilise whole blood in the tube at point of collection with CE-mark and FDA marketing clearance. The standardisation and stability it provides is especially important in clinical situations where multiple sites, transport times and reproducibility are key issues. The PAXgene blood collection tube contains a reagent which immediately stabilises intracellular RNA for up to three days at room temperature and up to 50 months at -20 to -70 °C. The ability to store and archive samples minimises the urgency to process them, thus enhancing laboratory efficiency.

The PAXgene purification process is designed to provide high-quality intracellular RNA from samples stabilised in the PreAnalytiX reagent. Using the PAXgene Blood RNA System on the QIAcube provides users with an integrated, automated approach to RNA purification.

The PAXgene Blood RNA Kit (50) is available in the US and Canada as version 762164 and in other countries as CE version 762174.