Kamiya Biomedical K-ASSAY Metallothionein (MT) I/II ELISA

Metallothionein (MT) is a family of cysteine-rich, low molecular weight proteins. MTs have the capacity to bind heavy metals through the thiol group of its cysteine residues. MTs play an important role in metal ion binding and in controlling biological systems. Research has linked MTs to many life science fields including cancer, chemotherapeutic drug resistance, oxidative stress, autism, immunology, toxicology, liver diseases, Alzheimer’s disease, Parkinson’s disease, Menke’s disease, Pick’s disease and Wilson’s disease.

Kamiya Biomedical’s K-ASSAY Metallothionein I/II ELISA is claimed to offer the widest assay range of any MT ELISA kit (640 to 10,000,000 pg/mL). It is specifically designed to measure native human and animal MT I and MT II. Unlike many other MT ELISAs, the kit uses antibodies against native MT, and not recombinant MT. The MT antibodies used in the kit have epitopes at the MT’s NH2-terminal acetylated-peptides.

Many other MT ELISA kits only react with their recombinant MT standard, not with actual native human and animal MT. The K-ASSAY Metallothionein I/II ELISA is confirmed to react with native MT I and MT II in human, rabbit, mouse, rat, fish and other animal species.