Labnet International MultiGene Gradient Thermal Cycler

Labnet International’s MultiGene Gradient Thermal Cycler has a large, backlit LCD displaying alphanumeric characters and a graphical representation of program steps with on-screen instructions for the programming process.

The cycler has common pre-programmed protocols, edited by moving to the appropriate parameter with the arrow keys and entering a new value. A maximum of 99 programs may be stored and organised in public or user folders, which can be password protected.

A variety of applications, from single temperature soaks to sophisticated multistep programs, can be simply set up. Time or temperature of a cycling step can be automatically increased or decreased during successive cycles, useful for touchdown applications and extending annealing times as enzyme is depleted.

Programs may be paused while running and, during operation, actual times and temperatures are displayed. Estimated run times are automatically calculated and a log of the last run can be displayed or downloaded.

The block can be programmed to operate with uniform temperature across the block or with a temperature gradient for protocol optimisation. Its gradient is spread horizontally allowing 12 temperatures to be evaluated simultaneously. To program a gradient, the high and low temperatures are set and the software automatically calculates and displays the temperature in each row. A maximum spread of 24ºC can be set up across the block.

The standard 96-well format block is easily removed and replaced, allowing the user to change block formats without changing cyclers.