NanoAnalytics cellZscopeE for automated TER measurement

The cellZscopeE, from NanoAnalytics, measures the TER and the capacitance of cell layers under physiological conditions. It is suitable for entry-level systems for computer-controlled TER (transepithelial/-endothelial resistance) measurements. TER of the cell layers under investigation is determined in real time and long-term measurements over days and weeks can also be carried out.

The good performance, instrument operations and easy maintenance make the product suitable for controlling the confluence of cell layers as well as for studying the influence of substances on the barrier function. It sweeps over a wide frequency range instead of simply measuring at a few frequency points. This provides unambiguous detection of cell layer properties.

The product is compatible with a variety of standard cell culture inserts from different manufacturers; the cell module can be loaded with six inserts simultaneously. Three versions of the electrodes are available, tailored for use with small (24-well), mid-sized (12-well) or large (6-well) inserts, respectively. Different well sizes can be combined within one cell module. The time resolution per well is 1 datapoint/h.