Navinci Diagnostics Naveni CD8/MHC-I Atto647N proximity ligation assay (PLA) kit

The Naveni CD8/MHC-I Atto647N is an in situ proximity ligation assay kit for the detection of the interaction of CD8 and MHC-I. This in situ kit is designed to give a high signal-to-noise ratio and have outstanding specificity. The kit is compatible with immunofluorescence co-staining for visualisation of the tumour microenvironment. The kit has been validated on FFPE human tissue samples. It is not recommended for mouse tissue and is for research use only — not for use in diagnostic procedures.

The kit is built upon Naveni in situ proximity ligation technology, featuring two Navenibodies linked to proprietary oligo arms. This technology is designed to ensure precise and sensitive detection. The primary antibodies included in the kit bind to CD8 and MHC-I proteins, while Navenibodies then bind to their respective primary antibodies. When Navenibodies are in close proximity, a strong and distinct signal is generated, offering a specific and sensitive detection method for the interaction between CD8 and MHC-I.

Navinci’s Naveni CD8/MHC-I Atto647N in situ Proximity Ligation Assay Kit is distributed in Australia and New Zealand by Sapphire Bioscience.