Navinci Diagnostics Naveni PD1/PD-L1 AP proximity ligation assay (PLA) kit

The Naveni PD1/PD-L1 AP is an in situ proximity ligation assay (PLA) kit for chromogenic and brightfield detection of the interaction of PD1 and PD-L1. A commercial assay for detecting the interaction in situ, the kit gives a high signal-to-noise ratio and has good specificity. It utilises alkaline phosphatase (AP) as the substrate and has been validated on formalin-fixed paraffin-embedded (FFPE) human tissue samples.

The kit is based on Navinci’s Naveni Proximity Ligation Technology, with two Navenibodies conjugated to proprietary oligo arms. The technology offers specific and sensitive detection.

One Navenibody binds the PD1 protein, and the other Navenibody binds PD-L1. Probes in close proximity will give a strong and distinct signal, creating a specific and sensitive detection method for the interaction between PD1 and PD-L1.