Navinci Diagnostics Naveni pY EGFR in situ proximity ligation assay kit

The Naveni pY EGFR is an in situ proximity ligation assay (PLA) kit for fluorescence detection of phosphorylated EGFR. The kit gives a high signal-to-noise ratio and is easily quantifiable, contrary to traditional immunofluorescence.

The kit is based on Navinci Diagnostics’ Naveni Proximity Ligation Technology, with two Navenibodies conjugated to proprietary oligo arms. The technology enables specific and sensitive detection.

The Navenibodies target two epitopes on the phosphorylated EGFR. One Navenibody targets the protein close to the cytoplasmic C-terminal and the other Navenibody interacts with phosphorylated tyrosine residues. Probes in close proximity will give rise to a strong and distinct signal, creating a specific and sensitive detection method for phosphorylated EGFR.

The kit is optimised for cell samples, and everything is included.