Navinci NaveniFlex Tissue Red proximity ligation assay kit

Navinci’s NaveniFlex Tissue Red is an in situ proximity ligation assay kit optimised for tissue samples. The kit enables fluorescence visualisation of protein–protein interactions or post-translational modifications such as phosphorylation and enables high specificity when localising single proteins. It should be used with the user’s primary antibodies of choice (raised in mouse and rabbit).

The product has been validated on FFPE and fresh frozen human and mouse tissue sections. It has been validated on several types of tissues, both healthy and cancerous, eg, colon, tonsil, ovary, kidney, breast, spleen, brain and skin.

Compatible with traditional immunostaining equipment, the kit uses secondary antibody detection to produce an amplified signal in the form of a fluorescent dot, thus facilitating the quantification of the readout. It is based on Navinci Diagnostics’ Naveni in situ proximity ligation technology, with two Navenibodies conjugated to proprietary oligo arms.

The kit is distributed in Australia and New Zealand by Sapphire Bioscience.