Qiagen GeneRead DNAseq V2 gene panels

Wednesday, 16 July, 2014 | Supplied by: QIAGEN Pty Ltd

Qiagen has launched 14 GeneRead DNAseq V2 gene panels targeting an extensive range of cancer-related genes and gene regions, including ‘focused’ panels each targeting 8-25 genes, ‘disease-specific’ panels for 40-50 genes and ‘comprehensive’ panels for as many as 160 genes.

The content of the panels has been developed based on the latest recommendations from relevant medical and scientific literature. The gene panels are integrated with Qiagen’s bioinformatics software, Ingenuity Variant Analysis, a curated database of gene variants and clinical data that enables interpretation of NGS results and delivers insights from sequencing data. Laboratories can customise the panels for specific disease pathways or research needs by tapping into Qiagen’s molecular content portfolio through GeneGlobe, an online portal covering more than 60,000 annotated molecular assays.

The technology provides a time-efficient approach for target enrichment in preparation for NGS runs on any sequencer. The panels use as little as 10 ng of starting DNA material per pool, are compatible with FFPE samples and do not require any specialised instruments. The algorithms and chemistry provide good coverage (>96% of coding regions), specificity (>90% of reads on target) and uniformity (>90% of bases are covered by at least 20% of the mean coverage depth) for the targeted DNA sequencing. The panels require only 3 h to enrich for targets and provide for a reduced time to go from isolated DNA sample to sequencing-ready libraries.

Online: www.qiagen.com
Phone: 03 9840 9800
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