Roche Cedex Bio Bioprocess Analyzer

The Roche Cedex Bio Bioprocess Analyzer is a continuous random-access analyser, enabling a safe and reliable determination of chemical and biochemical parameters in aqueous solutions. The compact desktop system is designed to fulfil the essential needs for metabolite screening and substrate analysis of bioprocesses.

Its comprehensive testing capabilities include photometric testing and electrolyte testing. The measurement of up to 14 parameters simultaneously (out of 28 programmable tests) is possible per sample.

The Cedex Bio Bioprocess Analyzer is easy to operate, enabling continuous loading and unloading of diverse cup types as well as onboard dilution of highly concentrated samples.

New parameters can be implemented by ‘plug and play’ and a development channel for individual assay customisation is planned.

Bioprocess analytics are performed throughout the process from cell line development to large-scale manufacturing of commercialised therapeutics. The majority of testing takes place during the upscale from plate-size to pre-clinical or early clinical studies supply – this is where the Cedex Bio Bioprocess Analyzer fits in. It is an accurate and reliable tool, providing bioprocess metabolite profiling, which is critical for the optimal production of biotherapeutics.

The Cedex Bio Analyzer was developed utilising the proven cobas Instrument technology from Roche.

Assays for the determination of glucose, lactate, LDH, NH₃, Na⁺, K⁺, glutamine and glutamate are available with the instrument. LDH as a parameter for cell death is unique in the metabolite profiling. Parameters like an IgG measurement with comparable precision to HPLC analysis will be available, soon.

The product is for life science research only and not for use in diagnostic procedures.