Sigma Life Science offers an enhanced version of its comprehensive online qPCR assay design tool - OligoArchitect. It is a freely available online tool for the automated design of primers and probes for quantitative real-time PCR assays.
Powered by the industry-standard Beacon Designer platform from Premier Biosoft, the product supports researchers’ easy use of Sigma Life Science’s qPCR probes, reagents and oligonucleotide services.
The easy-to-use software is now able to create designs with locked nucleic acid (LNA) for dual-labelled probes, molecular beacons and LightCycler probes. LNA is a DNA base modification that increases thermal stability and hybridisation specificity, which in turn allows for easier and more specific designs for problematic target sequences.
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